ROCCHETTI, MARCELLA
ROCCHETTI, MARCELLA
DIPARTIMENTO DI BIOTECNOLOGIE E BIOSCIENZE
In-vitro studies of the NaV1.5 S805L Brugada mutation: The resting cell voltage is a critical element in determining the pathological or physiological phenotype of the current
2024 Molla, D; Frosio, A; Bertoli, G; Piantoni, C; Arici, M; Bartolucci, C; Marchese, P; Bazzini, C; Barbuti, A; Rocchetti, M; Severi, S; Bucchi, A; Baruscotti, M
INTRACELLULAR Ca 2+ DYNAMICS MODULATION BY ISTAROXIME AND ITS METABOLITE IN PULMONARY ARTERY SMOOTH MUSCLE CELLS
2024 Metallo, A; D’Angeli, V; Arici, M; Rocchetti, M
Intracellular Ca2+ dynamics modulation by istaroxime and its metabolite in pulmonary artery smooth muscle cells.
2024 Metallo, A; D'Angeli, V; Arici, M; Rocchetti, M
Istaroxime follow-on compounds: A new class of selective SERCA2a activators for chronic heart failure treatment
2024 Arici, M; Hsu, S; Ferrandi, M; Barassi, P; Ronchi, C; Torre, E; Luraghi, A; Metallo, A; Chang, G; Ferrari, P; Bianchi, G; Regonesi, M; Airoldi, C; Peri, F; Zaza, A; Rocchetti, M
Selective SERCA2a activator as a candidate for chronic heart failure therapy
2024 Arici, M; Hsu, S; Ferrandi, M; Barassi, P; Ronchi, C; Torre, E; Luraghi, A; Chang, G; Ferrari, P; Bianchi, G; Peri, F; Zaza, A; Rocchetti, M
Striatin knock out induces a gain of function of INa and impaired Ca2+ handling in mESC‐derived cardiomyocytes
2024 Benzoni, P; Arici, M; Giannetti, F; Cospito, A; Prevostini, R; Volani, C; Fassina, L; Rosato‐siri, M; Metallo, A; Gennaccaro, L; Suffredini, S; Foco, L; Mazzetti, S; Calogero, A; Cappelletti, G; Leibbrandt, A; Elling, U; Broso, F; Penninger, J; Pramstaller, P; Piubelli, C; Bucchi, A; Baruscotti, M; Rossini, A; Rocchetti, M; Barbuti, A
A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes
2023 Altomare, C; Bartolucci, C; Sala, L; Balbi, C; Burrello, J; Pietrogiovanna, N; Burrello, A; Bolis, S; Panella, S; Arici, M; Krause, R; Rocchetti, M; Severi, S; Barile, L
Istaroxime Metabolite PST3093 Selectively Stimulates SERCA2a and Reverses Disease-Induced Changes in Cardiac Function
2023 Arici, M; Ferrandi, M; Barassi, P; Hsu, S; Torre, E; Luraghi, A; Ronchi, C; Chang, G; Peri, F; Ferrari, P; Bianchi, G; Rocchetti, M; Zaza, A
Recombinant hSERCA2a in yeast microsomes: a new tool for mechanistic studies on drug-induced SERCA2a stimulation
2023 Arici, M; Aspetti, C; Metallo, A; Regonesi, M; Airoldi, C; Rocchetti, M
Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure
2022 Luraghi, A; Ferrandi, M; Barassi, P; Arici, M; Hsu, S; Torre, E; Ronchi, C; Romerio, A; Chang, G; Ferrari, P; Bianchi, G; Zaza, A; Rocchetti, M; Peri, F
Istaroxime metabolite PST3093 selectively stimulates SERCA2a and reverses disease-induced changes in cardiac function
2022 Arici, M; Ferrandi, M; Hsu, S; Torre, E; Barassi, P; Luraghi, A; Ronchi, C; Chang, G; Peri, F; Ferrari, P; Bianchi, G; Rocchetti, M; Zaza, A
Liraglutide preserves CD34+ stem cells from dysfunction Induced by high glucose exposure
2022 Sforza, A; Vigorelli, V; Rurali, E; Perrucci, G; Gambini, E; Arici, M; Metallo, A; Rinaldi, R; Fiorina, P; Barbuti, A; Raucci, A; Sacco, E; Rocchetti, M; Pompilio, G; Genovese, S; Vinci, M
SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy
2022 Torre, E; Arici, M; Lodrini, A; Ferrandi, M; Barassi, P; Hsu, S; Chang, G; Boz, E; Sala, E; Vagni, S; Altomare, C; Mostacciuolo, G; Bussadori, C; Ferrari, P; Bianchi, G; Rocchetti, M
Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging
2022 Lazzarini, E; Lodrini, A; Arici, M; Bolis, S; Vagni, S; Panella, S; Rendon-Angel, A; Saibene, M; Metallo, A; Torre, T; Vassalli, G; Ameri, P; Altomare, C; Rocchetti, M; Barile, L
Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation
2021 Lavra, L; Magi, F; Ulivieri, A; Morgante, A; Paulis, M; Sala, L; Pedrazzini, M; Polisca, P; Rocchetti, M; Calo, L; Sciacchitano, S; Salehi, L
Intracellular Ca2+ dynamics in isolated Vascular Smooth Muscle Cells (VSMCs) from rat distal pulmonary artery through a non enzimatic method
2021 Arici, M; Ferrandi, M; Barassi, P; Citterio, S; Valtorta, C; Bazzu, C; Rocchetti, M
MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes
2021 Lee, Y; Sala, L; Mura, M; Rocchetti, M; Pedrazzini, M; Ran, X; Mak, T; Crotti, L; Sham, P; Torre, E; Zaza, A; Schwartz, P; Tse, H; Gnecchi, M
NOS1AP polymorphisms reduce NOS1 activity and interact with prolonged repolarization in arrhythmogenesis
2021 Ronchi, C; Bernardi, J; Mura, M; Stefanello, M; Badone, B; Rocchetti, M; Crotti, L; Brink, P; Schwartz, P; Gnecchi, M; Zaza, A
SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy (DCM)
2021 Torre, E; Arici, M; Lodrini, A; Ferrandi, M; Barassi, P; Hsu, S; Chang, G; Altomare, C; Ferrari, P; Bianchi, G; Rocchetti, M
Structural and Electrophysiological Changes in a Model of Cardiotoxicity Induced by Anthracycline Combined With Trastuzumab
2021 Altomare, C; Lodrini, A; Milano, G; Biemmi, V; Lazzarini, E; Bolis, S; Pernigoni, N; Torre, E; Arici, M; Ferrandi, M; Barile, L; Rocchetti, M; Vassalli, G