SALA, LUCA
SALA, LUCA
DIPARTIMENTO DI BIOTECNOLOGIE E BIOSCIENZE
Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications
2024 Prondzynski, M; Pioner, J; Sala, L; Bellin, M; Meraviglia, V
Geneless optomodulation of cardiomyocytes membrane potential by sarcolemma-targeted azobenzene photoswitches
2024 Florindi, C; Vurro, V; Ronchi, C; Sesti, V; Sala, L; Di Pasquale, E; Bertatelli, C; Antognazza, M; Zaza, A; Lanzani, G; Lodola, F
The Dynamic Clamp Technique: A Robust Toolkit for Investigating Potassium Channel Function
2024 Bartolucci, C; Sala, L
Therapeutic Efficacy of Mexiletine for Long QT Syndrome Type 2: Evidence from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Transgenic Rabbits, and Patients
2024 Crotti, L; Neves, R; Dagradi, F; Musu, G; Giannetti, F; Bos, J; Barbieri, M; Cerea, P; Giovenzana, F; Torchio, M; Mura, M; Gnecchi, M; Conte, G; Auricchio, A; Sala, L; Odening, K; Ackerman, M; Schwartz, P
Use of hiPSC-derived cardiomyocytes to study LQTS-variant specific proarrhythmic effects of drugs
2024 Sala, L; Khudiakov, A; Mura, M; Leonov, V; Giannetti, F; Crotti, L; Gnecchi, M; Schwartz, P
A dynamic clamping approach using in silico IK1 current for discrimination of chamber-specific hiPSC-derived cardiomyocytes
2023 Altomare, C; Bartolucci, C; Sala, L; Balbi, C; Burrello, J; Pietrogiovanna, N; Burrello, A; Bolis, S; Panella, S; Arici, M; Krause, R; Rocchetti, M; Severi, S; Barile, L
Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry
2023 Crotti, L; Spazzolini, C; Nyegaard, M; Overgaard, M; Kotta, M; Dagradi, F; Sala, L; Aiba, T; Ayers, M; Baban, A; Barc, J; Beach, C; Behr, E; Bos, J; Cerrone, M; Covi, P; Cuneo, B; Denjoy, I; Donner, B; Elbert, A; Eliasson, H; Etheridge, S; Fukuyama, M; Girolami, F; Hamilton, R; Horie, M; Iascone, M; Jaimez, J; Jensen, H; Kannankeril, P; Kaski, J; Makita, N; Muñoz-Esparza, C; Odland, H; Ohno, S; Papagiannis, J; Porretta, A; Prandstetter, C; Probst, V; Robyns, T; Rosenthal, E; Rosés-Noguer, F; Sekarski, N; Singh, A; Spentzou, G; Stute, F; Tfelt-Hansen, J; Till, J; Tobert, K; Vinocur, J; Webster, G; Wilde, A; Wolf, C; Ackerman, M; Schwartz, P
Continuous Bayesian Variant Interpretation Accounts for Incomplete Penetrance among Mendelian Cardiac Channelopathies
2023 O'Neill, M; Sala, L; Denjoy, I; Wada, Y; Kozek, K; Crotti, L; Dagradi, F; Kotta, M; Spazzolini, C; Leenhardt, A; Salem, J; Kashiwa, A; Ohno, S; Tao, R; Roden, D; Horie, M; Extramiana, F; Schwartz, P; Kroncke, B
Gene- and variant-specific efficacy of serum/glucocorticoid-regulated kinase 1 inhibition in long QT syndrome types 1 and 2
2023 Giannetti, F; Barbieri, M; Shiti, A; Casini, S; Sager, P; Das, S; Pradhananga, S; Srinivasan, D; Nimani, S; Alerni, N; Louradour, J; Mura, M; Gnecchi, M; Brink, P; Zehender, M; Koren, G; Zaza, A; Crotti, L; Wilde, A; Schwartz, P; Remme, C; Gepstein, L; Sala, L; Odening, K
Geneless optomodulation of cardiomyocytes membrane potential by membrane-targeted azobenzene photoswitches
2023 Florindi, C; Vurro, V; Ronchi, C; Sesti, V; Sala, L; Di Pasquale, E; Bertatelli, C; Antognazza, M; Zaza, A; Lanzani, G; Lodola, F
The impact of genetics on the long QT syndrome: myth or reality?
2023 Schwartz, P; Sala, L
Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19
2022 Sala, L; Leonov, V; Mura, M; Giannetti, F; Khudiakov, A; Moretti, A; Crotti, L; Gnecchi, M; Schwartz, P
Cardiac microtissues from human pluripotent stem cells recapitulate the phenotype of long-QT syndrome
2021 Giacomelli, E; Sala, L; Oostwaard, D; Bellin, M
Estimating the Posttest Probability of Long QT Syndrome Diagnosis for Rare KCNH2 Variants
2021 Kozek, K; Wada, Y; Sala, L; Denjoy, I; Egly, C; O'Neill, M; Aiba, T; Shimizu, W; Makita, N; Ishikawa, T; Crotti, L; Spazzolini, C; Kotta, M; Dagradi, F; Castelletti, S; Pedrazzini, M; Gnecchi, M; Leenhardt, A; Salem, J; Ohno, S; Zuo, Y; Glazer, A; Mosley, J; Roden, D; Knollmann, B; Blume, J; Extramiana, F; Schwartz, P; Horie, M; Kroncke, B
Generation and characterization of the human induced pluripotent stem cell (hiPSC) line NCUFi001-A from a patient carrying KCNQ1 G314S mutation
2021 Lavra, L; Magi, F; Ulivieri, A; Morgante, A; Paulis, M; Sala, L; Pedrazzini, M; Polisca, P; Rocchetti, M; Calo, L; Sciacchitano, S; Salehi, L
MTMR4 SNVs modulate ion channel degradation and clinical severity in congenital long QT syndrome: insights in the mechanism of action of protective modifier genes
2021 Lee, Y; Sala, L; Mura, M; Rocchetti, M; Pedrazzini, M; Ran, X; Mak, T; Crotti, L; Sham, P; Torre, E; Zaza, A; Schwartz, P; Tse, H; Gnecchi, M
Precision Medicine and cardiac channelopathies: When dreams meet reality
2021 Gnecchi, M; Sala, L; Schwartz, P
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
2020 Giacomelli, E; Meraviglia, V; Campostrini, G; Cochrane, A; Cao, X; van Helden, R; Krotenberg Garcia, A; Mircea, M; Kostidis, S; Davis, R; van Meer, B; Jost, C; Koster, A; Mei, H; Miguez, D; Mulder, A; Ledesma-Terron, M; Pompilio, G; Sala, L; Salvatori, D; Slieker, R; Sommariva, E; de Vries, A; Giera, M; Semrau, S; Tertoolen, L; Orlova, V; Bellin, M; Mummery, C
Isogenic Sets of hiPSC-CMs Harboring Distinct KCNH2 Mutations Differ Functionally and in Susceptibility to Drug-Induced Arrhythmias
2020 Brandao, K; van den Brink, L; Miller, D; Grandela, C; van Meer, B; Mol, M; de Korte, T; Tertoolen, L; Mummery, C; Sala, L; Verkerk, A; Davis, R
A platform for assessing pro- and anti-arrhythmic effects of drugs based on isogenic human iPSC-derived cardiomyocytes
2019 Campostrini, G; Sala, L; Ward-van Oostwaard, D; van Meer, B; Tertoolen, L; Bartulos-Encinas, O; Braam, S; Ijzerman, A; Mummery, C; Bellin, M