LEONI, VALERIO
 Distribuzione geografica
Continente #
NA - Nord America 6.530
EU - Europa 2.626
AS - Asia 1.509
AF - Africa 14
SA - Sud America 13
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 4
Totale 10.704
Nazione #
US - Stati Uniti d'America 6.482
IT - Italia 643
SG - Singapore 603
IE - Irlanda 483
CN - Cina 400
DE - Germania 375
SE - Svezia 361
RU - Federazione Russa 344
HK - Hong Kong 305
GB - Regno Unito 122
ID - Indonesia 93
UA - Ucraina 91
FR - Francia 55
CA - Canada 47
FI - Finlandia 39
JP - Giappone 30
VN - Vietnam 24
IN - India 22
NL - Olanda 22
AT - Austria 16
DK - Danimarca 14
BR - Brasile 12
RO - Romania 11
ES - Italia 10
CH - Svizzera 9
AU - Australia 8
KR - Corea 8
PL - Polonia 8
CZ - Repubblica Ceca 7
EG - Egitto 6
NO - Norvegia 6
BE - Belgio 5
NG - Nigeria 5
TR - Turchia 5
IL - Israele 4
EU - Europa 3
PH - Filippine 3
KW - Kuwait 2
PK - Pakistan 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AZ - Azerbaigian 1
CY - Cipro 1
GR - Grecia 1
IQ - Iraq 1
IR - Iran 1
KH - Cambogia 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
LU - Lussemburgo 1
MA - Marocco 1
MU - Mauritius 1
MX - Messico 1
MY - Malesia 1
SC - Seychelles 1
Totale 10.704
Città #
Ann Arbor 1.140
Fairfield 972
Singapore 551
Dublin 468
Wilmington 465
Woodbridge 429
Ashburn 420
Seattle 375
Houston 353
Cambridge 337
Frankfurt am Main 300
Hong Kong 295
Santa Clara 247
Milan 215
Chandler 193
Princeton 192
New York 168
Dearborn 142
Altamura 93
Jakarta 93
Lawrence 93
San Diego 85
Jacksonville 74
Shanghai 58
Nanjing 52
Beijing 39
Andover 33
London 31
Toronto 29
Helsinki 27
Chicago 21
Guangzhou 20
Shenyang 18
Rome 17
Desio 16
Monza 16
Nanchang 16
Hefei 15
Redmond 14
Chengdu 13
Dong Ket 13
Ottawa 13
Hebei 12
Lappeenranta 12
Los Angeles 12
Vienna 12
Boardman 11
Hangzhou 11
Jinan 11
Paris 11
Cinisello Balsamo 10
Munich 10
Pune 10
Tianjin 10
Jiaxing 9
Mariano Comense 9
São Paulo 8
Amsterdam 7
Brno 7
Changsha 7
Florence 7
Huizen 7
San Mateo 7
Somerville 7
Bonndorf 6
Cairo 6
Fremont 6
Romola 6
Tokyo 6
Biassono 5
Bologna 5
Brooklyn 5
Calestano 5
Central 5
Cluj-Napoca 5
Falls Church 5
Induno Olona 5
Shenzhen 5
Xiamen 5
Brentford 4
Carate Brianza 4
Caserta 4
Cheongju-si 4
Council Bluffs 4
Dallas 4
Guilin 4
Hanover 4
Kilburn 4
Kunming 4
Lyon 4
Marietta 4
Montreal 4
Moscow 4
Osaka 4
Stanford 4
Tappahannock 4
Warsaw 4
Washington 4
Ås 4
Buffalo 3
Totale 8.531
Nome #
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy 363
A microglial cell model for acyl-CoA oxidase 1 deficiency 284
4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas 218
DNA damage in circulating hematopoietic progenitor stem cells as promising biological sensor of frailty 198
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients 193
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected 191
On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review) 175
Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration 171
Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2 157
Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection 156
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study 141
Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice 135
Effect of industrial processing and storage procedures on oxysterols in milk and milk products 135
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol 134
Oxysterols and Alzheimer's disease 132
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense 129
Diagnostic use of cerebral and extracerebral oxysterols 126
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress 125
Spheroplasts, poorly known but clinically relevant particles of urinary sediment 125
Octadecaneuropeptide (ODN) induces N2a cells differentiation through a PKA/PLC/PKC/MEK/ERK-dependent pathway: Incidence on peroxisome, mitochondria, and lipid profiles 124
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes 124
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods 122
Antiviral oxysterols are present in human milk at diverse stages of lactation 120
Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays 120
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers 119
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis 118
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice 117
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease 116
Genetic connections between neurological disorders and cholesterol metabolism 116
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma 116
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes 115
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders 115
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes 114
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis 111
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis 110
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors 110
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation 109
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study 109
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases 107
Oxysterols and neurodegenerative diseases 106
Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers 103
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol 102
Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers 102
Oxysterols as markers of neurological disease--a review 101
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease 101
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol 99
The impairment of cholesterol metabolism in Huntington disease 98
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease 98
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice 98
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice 98
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? 96
Biological variation of Serum Amyloid A in healthy subjects 96
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease 96
Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms 95
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease 95
Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer 95
NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease 95
Study of cholesterol metabolism in Huntington's disease 94
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods 94
A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats 93
Whole body cholesterol metabolism is impaired in Huntington's disease 91
Intestinal permeability and Ménière's disease 91
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations 90
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period 90
Oxysterols as biomarkers in neurodegenerative diseases 88
Potential diagnostic applications of side chain oxysterols analysis in plasma and cerebrospinal fluid 88
Somatosensory conduction pathway in spastic paraplegia type 5 88
Sex‐difference in flux of 27‐hydroxycholesterol in the brain 88
Biomarker report from the phase II lamotrigine trial in secondary progressive MS – neurofilament as a surrogate of disease progression 84
PEX7 mutations cause congenital cataract retinopathy and late-onset ataxia and cognitive impairment: Report of two siblings and review of the literature 82
Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression 82
Glucose accelerates copper- and ceruloplasmin-induced oxidation of low-density lipoprotein and whole serum 82
Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy 81
Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice 81
Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion 80
Relationship between cholesterol metabolism, ApoE and brain volumes in Alzheimer’s disease 80
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fi ction? 79
Pitfalls in the detection of cholesterol in Huntington's disease models 78
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease 77
Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis 76
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease 76
Cholesterol metabolism in Huntington’s Disease 74
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health 71
Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients 70
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period 69
Cerebral and extracerebral cholesterol biosynthesis is impaired in HD patients 66
Identification of SARS-CoV-2 positivity using machine learning methods on blood count data: External validation of state-of-the-art models. [Identificazione di positività al SARS-CoV-2 attraverso metodi di Machine Learning sui dati dell'esame emocromocitometrico: Validazione esterna di modelli allo stato dell'arte] 63
Links between ApoE, brain cholesterol metabolism, tau and amyloid β-peptide in patients with cognitive impairment 60
Peroxisome-Proliferator-Activated Receptor Gamma Coactivator 1 alpha Contributes to Dysmyelination in Experimental Models of Huntington's Disease 59
7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19 59
Oxysterols and cholesterol metabolism in neurodegenerative disease. A metabolic approach 57
Role of 27-hydroxycholesterol and its metabolism in cancer progression: Human studies 56
Oxysterols: From redox bench to industry 50
Unraveling the complexity of anti-doping analysis: reassessing meldonium detection and doping verdicts in a case study 44
In vitro antimicrobial activity of the siderophore cephalosporin cefiderocol against acinetobacter baumannii strains recovered from clinical samples 44
24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2 43
Antibody response after two doses of the SARS-CoV-2 Comirnaty vaccine in a Covid-19 positive and Covid-19 negative Italian healthcare workers cohort 43
Presence of cholesterol oxides in milk chocolates and their correlation with milk powder freshness 43
ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis 43
Metabolic Consequences Of Coenzyme A Deficiency In Patients With Pank2 Mutations 42
Totale 10.463
Categoria #
all - tutte 49.965
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.965


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.241 0 0 0 0 0 291 283 215 208 115 88 41
2020/20211.981 62 143 207 162 207 207 238 240 136 135 124 120
2021/20221.224 137 128 168 93 83 93 70 73 47 79 93 160
2022/20231.704 224 470 153 76 103 274 72 65 116 41 56 54
2023/20241.515 48 50 62 55 201 307 283 56 209 28 49 167
2024/20251.886 268 636 265 200 357 160 0 0 0 0 0 0
Totale 11.290