LEONI, VALERIO
 Distribuzione geografica
Continente #
NA - Nord America 6.724
EU - Europa 3.306
AS - Asia 2.129
SA - Sud America 173
AF - Africa 39
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 4
Totale 12.384
Nazione #
US - Stati Uniti d'America 6.667
SG - Singapore 901
IT - Italia 744
RU - Federazione Russa 727
HK - Hong Kong 551
IE - Irlanda 487
DE - Germania 450
CN - Cina 425
SE - Svezia 365
BR - Brasile 158
GB - Regno Unito 123
UA - Ucraina 116
ID - Indonesia 94
FR - Francia 63
CA - Canada 52
AT - Austria 48
FI - Finlandia 43
NL - Olanda 40
JP - Giappone 35
IN - India 29
VN - Vietnam 25
ZA - Sudafrica 19
DK - Danimarca 15
PL - Polonia 13
ES - Italia 12
RO - Romania 12
CH - Svizzera 11
TR - Turchia 11
MD - Moldavia 10
AU - Australia 9
CZ - Repubblica Ceca 8
KR - Corea 8
AR - Argentina 7
EG - Egitto 7
NO - Norvegia 6
UZ - Uzbekistan 6
BE - Belgio 5
IL - Israele 5
NG - Nigeria 5
AZ - Azerbaigian 4
MX - Messico 4
AE - Emirati Arabi Uniti 3
CO - Colombia 3
EC - Ecuador 3
EU - Europa 3
IQ - Iraq 3
IR - Iran 3
KW - Kuwait 3
MA - Marocco 3
PH - Filippine 3
PK - Pakistan 3
BD - Bangladesh 2
KE - Kenya 2
KZ - Kazakistan 2
LT - Lituania 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AM - Armenia 1
BG - Bulgaria 1
BO - Bolivia 1
CL - Cile 1
CY - Cipro 1
DZ - Algeria 1
GR - Grecia 1
JO - Giordania 1
KG - Kirghizistan 1
KH - Cambogia 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MU - Mauritius 1
MY - Malesia 1
OM - Oman 1
PA - Panama 1
PT - Portogallo 1
SC - Seychelles 1
TH - Thailandia 1
TJ - Tagikistan 1
TM - Turkmenistan 1
TW - Taiwan 1
Totale 12.384
Città #
Ann Arbor 1.140
Fairfield 972
Singapore 653
Hong Kong 539
Dublin 472
Wilmington 465
Ashburn 432
Woodbridge 430
Seattle 377
Houston 355
Cambridge 337
Frankfurt am Main 305
Milan 253
Santa Clara 244
Chandler 193
Princeton 192
New York 168
Dearborn 142
Altamura 93
Jakarta 93
Lawrence 93
San Diego 85
Jacksonville 74
Moscow 69
Shanghai 61
Nanjing 52
Beijing 42
Andover 33
Nuremberg 32
London 31
Vienna 31
Toronto 30
Monza 28
Helsinki 27
Chicago 24
Los Angeles 24
Rome 24
Guangzhou 22
Council Bluffs 21
São Paulo 19
Shenyang 18
Desio 16
Lappeenranta 16
Nanchang 16
Hefei 15
Chengdu 14
Ottawa 14
Redmond 14
Dong Ket 13
Paris 13
Hebei 12
Boardman 11
Hangzhou 11
Jinan 11
Chisinau 10
Cinisello Balsamo 10
Munich 10
Pune 10
Tianjin 10
Tokyo 10
Amsterdam 9
Bologna 9
Jiaxing 9
Mariano Comense 9
Brno 7
Changsha 7
Florence 7
Huizen 7
San Mateo 7
Somerville 7
Zhengzhou 7
Bonndorf 6
Cairo 6
Cologno Monzese 6
Fremont 6
Romola 6
Tashkent 6
Biassono 5
Brooklyn 5
Calestano 5
Central 5
Cluj-Napoca 5
Curitiba 5
Dallas 5
Falls Church 5
Induno Olona 5
Osaka 5
Phoenix 5
Shenzhen 5
Xiamen 5
Baku 4
Bodio Lomnago 4
Brentford 4
Carate Brianza 4
Caserta 4
Cheongju-si 4
Guilin 4
Hanover 4
Johannesburg 4
Kilburn 4
Totale 9.157
Nome #
CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy 395
A microglial cell model for acyl-CoA oxidase 1 deficiency 304
4-IPP, a selective MIF inhibitor, causes mitotic catastrophe in thyroid carcinomas 234
DNA damage in circulating hematopoietic progenitor stem cells as promising biological sensor of frailty 222
Bacterial and fungal colonization of the respiratory tract in COVID-19 patients should not be neglected 208
The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients 207
Surfactant protein D (SP-D) as a biomarker of SARS-CoV-2 infection 188
On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review) 184
Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2 177
Increased production of 27-hydroxycholesterol in human colorectal cancer advanced stage: Possible contribution to cancer cell survival and infiltration 176
Baseline characteristics of COVID-19 Italian patients admitted to Desio Hospital, Lombardy: a retrospective study 164
Oxysterols and Alzheimer's disease 147
Effect of industrial processing and storage procedures on oxysterols in milk and milk products 146
Diagnostic use of cerebral and extracerebral oxysterols 145
Purple corn extract induces long-lasting reprogramming and M2 phenotypic switch of adipose tissue macrophages in obese mice 145
Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol 142
Spheroplasts, poorly known but clinically relevant particles of urinary sediment 141
Monoclonal free light chain detection and quantification: Performances and limits of available laboratory assays 139
SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes 138
Modulation of cell proteome by 25-hydroxycholesterol and 27-hydroxycholesterol: A link between cholesterol metabolism and antiviral defense 136
Octadecaneuropeptide (ODN) induces N2a cells differentiation through a PKA/PLC/PKC/MEK/ERK-dependent pathway: Incidence on peroxisome, mitochondria, and lipid profiles 135
Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress 134
Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes 133
First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography–Urgent need for harmonisation of analytical methods 131
Antiviral oxysterols are present in human milk at diverse stages of lactation 130
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders 130
MIF/CD74 axis is a target for novel therapies in colon carcinomatosis 128
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers 126
Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice 125
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease 123
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes 123
Genetic connections between neurological disorders and cholesterol metabolism 123
Involvement of 27-Hydroxycholesterol in Mitotane Action on Adrenocortical Carcinoma 123
Antimicrobial Resistance Trends of Escherichia coli Isolates from Outpatient and Inpatient Urinary Infections over a 20-Year Period 122
Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with α-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, cholesterol and cholesterol precursors 120
Levels of 7-oxocholesterol in cerebrospinal fluid are more than one thousand times lower than reported in multiple sclerosis 119
24S-hydroxycholesterol in plasma: A marker of cholesterol turnover in neurodegenerative diseases 117
Oxysterols and neurodegenerative diseases 117
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation 117
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis 117
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study 117
Oxysterols as markers of neurological disease--a review 115
Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles for cholesterol delivery in Huntington's disease 114
Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice 113
Trend of 25-hydroxycholesterol and 27-hydroxycholesterol plasma levels in patients affected by active chronic hepatitis B virus infection and inactive carriers 113
Biological variation of Serum Amyloid A in healthy subjects 112
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol 111
Oxysterols and Parkinson's disease: evidence that levels of 24S-hydroxycholesterol in cerebrospinal fluid correlates with the duration of the disease 111
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol 107
Evidence for sex difference in the CSF/plasma albumin ratio in ~20 000 patients and 335 healthy volunteers 107
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease 106
International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods 106
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice 105
The impairment of cholesterol metabolism in Huntington disease 104
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? 104
Intestinal permeability and Ménière's disease 103
NAD(+)-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease 103
Sex‐difference in flux of 27‐hydroxycholesterol in the brain 103
Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms 102
Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease 102
Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer 102
Whole body cholesterol metabolism is impaired in Huntington's disease 102
A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats 100
Study of cholesterol metabolism in Huntington's disease 99
Oxysterols as biomarkers in neurodegenerative diseases 99
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations 99
Potential diagnostic applications of side chain oxysterols analysis in plasma and cerebrospinal fluid 98
Somatosensory conduction pathway in spastic paraplegia type 5 97
Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy 97
Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period 96
Unraveling the complexity of anti-doping analysis: reassessing meldonium detection and doping verdicts in a case study 93
Biomarker report from the phase II lamotrigine trial in secondary progressive MS – neurofilament as a surrogate of disease progression 93
Glucose accelerates copper- and ceruloplasmin-induced oxidation of low-density lipoprotein and whole serum 91
High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: Fact or fi ction? 90
Regular treadmill exercise inhibits mitochondrial accumulation of cholesterol and oxysterols during myocardial ischemia-reperfusion in wild-type and ob/ob mice 90
Plasma 24S-hydroxycholesterol correlation with markers of Huntington disease progression 89
PEX7 mutations cause congenital cataract retinopathy and late-onset ataxia and cognitive impairment: Report of two siblings and review of the literature 88
Pitfalls in the detection of cholesterol in Huntington's disease models 88
Relationship between cholesterol metabolism, ApoE and brain volumes in Alzheimer’s disease 86
The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease 86
Antimicrobial Resistance Patterns of Enterobacter cloacae and Klebsiella aerogenes Strains Isolated from Clinical Specimens: A Twenty-Year Surveillance Study 85
Upregulation of brain renin angiotensin system by 27-hydroxycholesterol in Alzheimer's disease 84
Cardioprotection by the TSPO ligand 4'-chlorodiazepam is associated with inhibition of mitochondrial accumulation of cholesterol at reperfusion 84
Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis 84
Cholesterol metabolism in Huntington’s Disease 82
Diagnostic power of 24S-hydroxycholesterol in cerebrospinal fluid: Candidate marker of brain health 82
Identification of SARS-CoV-2 positivity using machine learning methods on blood count data: External validation of state-of-the-art models. [Identificazione di positività al SARS-CoV-2 attraverso metodi di Machine Learning sui dati dell'esame emocromocitometrico: Validazione esterna di modelli allo stato dell'arte] 78
Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients 77
Cerebral and extracerebral cholesterol biosynthesis is impaired in HD patients 74
7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19 71
Peroxisome-Proliferator-Activated Receptor Gamma Coactivator 1 alpha Contributes to Dysmyelination in Experimental Models of Huntington's Disease 69
Cardiovascular Structural and Functional Parameters in Idiopathic Pulmonary Fibrosis at Disease Diagnosis 68
Oxysterols and cholesterol metabolism in neurodegenerative disease. A metabolic approach 66
Role of 27-hydroxycholesterol and its metabolism in cancer progression: Human studies 66
Links between ApoE, brain cholesterol metabolism, tau and amyloid β-peptide in patients with cognitive impairment 65
Antibody response after two doses of the SARS-CoV-2 Comirnaty vaccine in a Covid-19 positive and Covid-19 negative Italian healthcare workers cohort 65
24S-Hydroxycholesterol and Cerebellar Degeneration: Insights from SCA2 64
Oxysterols: From redox bench to industry 63
Oxysterols as Reliable Markers of Quality and Safety in Cholesterol Containing Food Ingredients and Products 61
The Diagnostic Use of the Plasma Quantification of 24S-Hydroxycholesterol and Other Oxysterols in Neurodegenerative Disease 59
Totale 11.719
Categoria #
all - tutte 58.192
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.192


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020244 0 0 0 0 0 0 0 0 0 115 88 41
2020/20211.981 62 143 207 162 207 207 238 240 136 135 124 120
2021/20221.224 137 128 168 93 83 93 70 73 47 79 93 160
2022/20231.704 224 470 153 76 103 274 72 65 116 41 56 54
2023/20241.515 48 50 62 55 201 307 283 56 209 28 49 167
2024/20253.718 268 636 265 200 353 191 375 127 568 735 0 0
Totale 13.122