LONGHESE, MARIA PIA
 Distribuzione geografica
Continente #
NA - Nord America 9.908
EU - Europa 5.949
AS - Asia 1.786
SA - Sud America 12
AF - Africa 8
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 4
Totale 17.674
Nazione #
US - Stati Uniti d'America 9.757
IT - Italia 1.709
DE - Germania 880
SE - Svezia 717
CN - Cina 638
PL - Polonia 600
SG - Singapore 468
IE - Irlanda 386
UA - Ucraina 317
RU - Federazione Russa 294
FR - Francia 292
GB - Regno Unito 278
HK - Hong Kong 247
VN - Vietnam 164
CA - Canada 149
AT - Austria 128
FI - Finlandia 114
DK - Danimarca 98
IN - India 94
TR - Turchia 69
ID - Indonesia 68
NL - Olanda 55
BE - Belgio 40
CH - Svizzera 10
JP - Giappone 9
EU - Europa 6
PK - Pakistan 6
BR - Brasile 5
CZ - Repubblica Ceca 5
GR - Grecia 5
IR - Iran 5
RS - Serbia 4
SC - Seychelles 4
AU - Australia 3
ES - Italia 3
PE - Perù 3
PH - Filippine 3
PT - Portogallo 3
BG - Bulgaria 2
EC - Ecuador 2
IL - Israele 2
KR - Corea 2
KZ - Kazakistan 2
MU - Mauritius 2
MY - Malesia 2
NO - Norvegia 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AR - Argentina 1
AZ - Azerbaigian 1
CL - Cile 1
CY - Cipro 1
EG - Egitto 1
HU - Ungheria 1
IQ - Iraq 1
IS - Islanda 1
JO - Giordania 1
KW - Kuwait 1
LV - Lettonia 1
MD - Moldavia 1
MK - Macedonia 1
MX - Messico 1
NZ - Nuova Zelanda 1
PA - Panama 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 17.674
Città #
Ann Arbor 2.426
Fairfield 931
Woodbridge 815
Chandler 659
Houston 649
Frankfurt am Main 623
Milan 621
Wilmington 603
Kraków 594
Ashburn 505
Singapore 389
Dublin 374
Seattle 364
Jacksonville 361
Cambridge 278
Dearborn 258
Hong Kong 247
New York 210
Santa Clara 206
Princeton 164
Dong Ket 128
Vienna 127
Nanjing 117
Altamura 92
Shanghai 89
Lawrence 81
Jakarta 65
San Diego 64
Lachine 55
Fremont 54
Guangzhou 52
Helsinki 50
Nanchang 48
Rome 48
Beijing 44
Boardman 44
Brussels 39
Ottawa 37
Toronto 30
Andover 29
Hebei 29
Los Angeles 28
Botticino 26
Huizen 26
Jinan 26
Kunming 22
London 22
Munich 22
Shenyang 21
Capralba 19
Falls Church 19
Zhengzhou 19
Seveso 18
Changsha 17
Cuggiono 17
Tianjin 17
Philadelphia 16
Sacramento 16
Chicago 15
Edmonton 15
Jiaxing 15
Brescia 14
Cinisello Balsamo 14
Taizhou 14
Auburn Hills 13
Montpellier 13
Mountain View 13
Sesto San Giovanni 13
Vedano al Lambro 13
Bonndorf 12
Kiev 12
Ningbo 12
Novate Milanese 12
Hefei 11
Norwalk 11
Dallas 10
Pavia 10
Rossiglione 10
Romola 9
Stockholm 9
Bologna 8
Grafing 8
Hangzhou 8
Leawood 8
New Delhi 8
Santa Cruz 8
Tappahannock 8
Torino 8
Verona 8
Changchun 7
Citta Sant'angelo 7
Seregno 7
Aarhus 6
Bournemouth 6
Carate Brianza 6
Como 6
Giussano 6
Kocaeli 6
Maierato 6
Montréal 6
Totale 13.361
Nome #
Structure–function relationships of the Mre11 protein in the control of DNA end bridging and processing 443
Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 Activity 418
DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends 403
Uncoupling Sae2 functions in downregulation of Tel1 and Rad53 signaling activities 402
The MRX complex regulates Exo1 resection activity by altering DNA end structure 384
Tel1/ATM Signaling to the Checkpoint Contributes to Replicative Senescence in the Absence of Telomerase 375
The ATP-bound conformation of the Mre11-Rad50 complex is essential for Tel1/ATM activation 371
Processing of DNA double-strand breaks by the MRX complex in a chromatin context 343
Structurally distinct Mre11 domains mediate MRX functions in resection, end-tethering and DNA damage resistance 336
Tel1/ATM prevents degradation of replication forks that reverse after topoisomerase poisoning 317
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks 309
Rad9/53BP1 protects stalled replication forks from degradation in Mec1/ATR-defective cells 293
Regulation of telomere metabolism by the RNA processing protein Xrn1 287
Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity 285
Resection of a DNA Double-Strand Break by Alkaline Gel Electrophoresis and Southern Blotting 283
Escape of Sgs1 from Rad9 inhibition reduces the requirement for Sae2 and functional MRX in DNA end resection 267
Coupling end resection with the checkpoint response at DNA double-strand breaks 264
Functions and regulation of the MRX complex at DNA double-strand breaks 264
Processing of DNA ends in the maintenance of genome stability 259
Distinct Cdk1 requirements during single-strand annealing, noncrossover and crossover recombination 246
DNA double-strand breaks in meiosis: Checking their formation, processing and repair 245
Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability 242
Tbf1 and Vid22 promote resection and non-homologous end joining of DNA double-strand break ends. 238
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends 232
The RNA binding protein Npl3 promotes resection of DNA double-strand breaks by regulating the levels of Exo1 231
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 224
A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres 223
The regulation of the DNA damage response at telomeres: Focus on kinases 222
Telomeres and DNA damage checkpoints 218
G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint. 218
Mechanisms and regulation of DNA end resection 213
The MRX complex plays multiple functions in resection of Yku- and Rif2-protected DNA ends 212
The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks 212
Interplays between ATM/Tel1 and ATR/Mec1 in sensing and signaling DNA double-strand breaks 211
Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae 211
The cellular response to chromosome breakage 209
RNA-processing proteins regulate Mec1/ATR activation by promoting generation of RPA-coated ssDNA 207
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression 204
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation. 204
The Yku70-Yku80 complex contributes to regulate double-strand break processing and checkpoint activation during the cell cycle 202
Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases 202
Rif1 supports the function of the CST complex in yeast telomere capping 200
How do cells sense DNA lesions? 198
Multiple pathways regulate 3’ overhang generation at S. cerevisiae telomeres 197
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway 196
Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks 192
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection 189
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint 186
Surveillance mechanisms monitoring chromosome breaks during mitosis and meiosis 184
functional and physical interactions between yeast 14-3-3 proteins, acetyltransferases, and deacetylases in response to DNA replication perturbations 184
Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes 184
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae 181
RPA regulates telomerase action by providing Est1p access to chromosome ends 180
Budding yeast Sae2 is an in vivo target of the Mec1 and Tel1 checkpoint kinases during meiosis 179
Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends 178
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. 177
The General Regulatory Factor Tbf1 and its interacting protein Vid22 promote repair of DNA double-strand breaks 175
The Saccharomyces cerevisiae 14-3-3 proteins are required for the G 1/S transition, actin cytoskeleton organization and cell wall integrity 172
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling 171
The functions of budding yeast Sae2 in the DNA damage response require Mec1- and Tel1-dependent phosphorylation 169
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. 168
Role of the Saccharomyces cerevisiae Rad53 checkpoint kinase in signaling double-strand breaks during the meiotic cell cycle. 166
A central role for DNA replication forks in checkpoint activation and response 165
Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae 160
Shelterin-like proteins and Yku inhibit nucleolytic processing of S. cerevisiae telomeres 159
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response 157
MRX-dependent DNA damage response to short telomeres 155
The set1Δ mutation unveils a novel signaling pathway relayed by the Rad53-dependent hyperphosphorylation of replication protein A that leads to transcriptional activation of repair genes 154
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing 153
DNA damage response at functional and dysfunctional telomeres 149
Telomere-end processing: mechanisms and regulation 149
The Mec1p and Tel1p checkpoint kinases allow humanized yeast to tolerate chronic telomere dysfunctions by suppressing telomere fusions 144
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners 142
Interplay between Sae2 and Rif2 in the regulation of Mre11-Rad50 activities at DNA ends 142
Dephosphorylation of γH2A by Gcl7/Protein Phosphatase 1 promotes recovery from inhibition of DNA replication 137
Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress 136
The role of shelterin in maintaining telomere integrity 136
Dominant TEL1-hy mutations compensate for Mec1 lack of functions in the DNA damage response 135
Regulation of the DNA damage response by cyclin-dependent kinases 134
The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks 130
Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding 119
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing 119
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase 114
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast. 112
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks 108
The DNA damage checkpoint: A tale from budding yeast 99
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation 89
Proteasome-mediated degradation of long-range nucleases negatively regulates resection of DNA double-strand breaks 50
Exo1 cooperates with Tel1/ATM in promoting recombination events at DNA replication forks 45
Functional and molecular insights into the role of Sae2 C-terminus in the activation of MRX endonuclease 8
Totale 18.455
Categoria #
all - tutte 53.909
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.909


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.562 0 0 0 0 0 0 427 234 281 344 194 82
2020/20212.901 114 119 264 288 243 278 244 245 239 344 168 355
2021/20221.907 167 214 296 200 125 147 107 95 64 88 179 225
2022/20232.737 281 782 283 295 181 367 32 147 196 36 102 35
2023/20241.740 61 71 46 124 190 419 299 194 112 26 41 157
2024/20251.481 185 327 245 173 265 169 117 0 0 0 0 0
Totale 18.455