Arterial hypertension is a major risk factor for cardiovascular disease. Despite treatment recommendations, including lifestyle changes and use of combination drug treatment, a consistent fraction of hypertensive patients fails to achieve adequate blood pressure targets recommended by current guidelines. In order to improve blood pressure control and to reduce cardiovascular events, renal artery denervation has been proposed as a non-pharmacological approach. Studies conducted over the years have initially produced conflicting results on the use of renal denervation and its application in routine antihypertensive treatment remains debated. However, recent trials using different devices have shown promising results in the treatment of patients with hypertension. Although long-term results are still needed to confirm the efficacy and safety of the procedure, renal denervation regarded as an useful approach in the treatment of selected patients with hypertension, including resistant and difficult-to-control hypertension.

Fosca, Q., Grassi, G. (2025). Renal Denervation. In A.E. Berbari, G. Mancia, J. Redon (a cura di), Blood pressure disorders in acute and chronic kidney disease (pp. 367-375). Springer [10.1007/978-3-031-81292-7_17].

Renal Denervation

Quarti-Trevano Fosca
;
Grassi Guido
2025

Abstract

Arterial hypertension is a major risk factor for cardiovascular disease. Despite treatment recommendations, including lifestyle changes and use of combination drug treatment, a consistent fraction of hypertensive patients fails to achieve adequate blood pressure targets recommended by current guidelines. In order to improve blood pressure control and to reduce cardiovascular events, renal artery denervation has been proposed as a non-pharmacological approach. Studies conducted over the years have initially produced conflicting results on the use of renal denervation and its application in routine antihypertensive treatment remains debated. However, recent trials using different devices have shown promising results in the treatment of patients with hypertension. Although long-term results are still needed to confirm the efficacy and safety of the procedure, renal denervation regarded as an useful approach in the treatment of selected patients with hypertension, including resistant and difficult-to-control hypertension.
Capitolo o saggio
renal denervation, chronic renal failure
English
Blood pressure disorders in acute and chronic kidney disease
Berbari, AE; Mancia, G; Redon, J
4-apr-2025
2025
9783031812910
Springer
367
375
Fosca, Q., Grassi, G. (2025). Renal Denervation. In A.E. Berbari, G. Mancia, J. Redon (a cura di), Blood pressure disorders in acute and chronic kidney disease (pp. 367-375). Springer [10.1007/978-3-031-81292-7_17].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/549021
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