Acute Respiratory Distress Syndrome (ARDS) is a complex and debilitating disease of the lungs, which continues to have a high mortality rate and huge disease burden on patients. Incidence is rising, possibly due to greater awareness leading to more diagnoses rather than a change in the underlying rate. It arises from multiple etiologies, though pathogenic infection, termed pneumonia, is the most prevalent and widely studied. The distinct pathophysiology and rapid evolution of ARDS makes it uniquely challenging with regard to therapeutics development and, to date, no medicines are licensed for specific therapy. Antibiotics, ventilation, and other organ support remain intervention standards.
Rezoagli, E., Murphy, E., Laffey, J., O'Toole, D. (2019). The safety and efficiency of addressing ards using stem cell therapies in clinical trials. In Burgess JK, Heijink I (a cura di), Stem Cell-Based Therapy for Lung Disease (pp. 219-238). Springer International Publishing [10.1007/978-3-030-29403-8_12].
The safety and efficiency of addressing ards using stem cell therapies in clinical trials
Rezoagli E.Primo
;
2019
Abstract
Acute Respiratory Distress Syndrome (ARDS) is a complex and debilitating disease of the lungs, which continues to have a high mortality rate and huge disease burden on patients. Incidence is rising, possibly due to greater awareness leading to more diagnoses rather than a change in the underlying rate. It arises from multiple etiologies, though pathogenic infection, termed pneumonia, is the most prevalent and widely studied. The distinct pathophysiology and rapid evolution of ARDS makes it uniquely challenging with regard to therapeutics development and, to date, no medicines are licensed for specific therapy. Antibiotics, ventilation, and other organ support remain intervention standards.File | Dimensione | Formato | |
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