The paper investigates the problem of tracking a desired level of plasma glucose concentration. The model for the glucose-insulin system considered here, and recently published, belongs to the class of single-distributed delay models. The control law is obtained according to the feedback linearization theory. Both the cases of hyperglycemic and hypoglycemic patients have been considered. Simulations support theoretical results and show the physical reliability of the approach proposed
Palumbo, P., De Gaetano, A. (2007). State-feedback control of the glucose-insulin system. In MATH EVERYWHERE. Deterministic and Stochastic Modelling in Biomedicine, Economics and Industry (pp. 241-252). Springer Berlin Heidelberg [10.1007/978-3-540-44446-6_20].
State-feedback control of the glucose-insulin system
Palumbo, P;
2007
Abstract
The paper investigates the problem of tracking a desired level of plasma glucose concentration. The model for the glucose-insulin system considered here, and recently published, belongs to the class of single-distributed delay models. The control law is obtained according to the feedback linearization theory. Both the cases of hyperglycemic and hypoglycemic patients have been considered. Simulations support theoretical results and show the physical reliability of the approach proposed
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