The first phosphorous chelate chiral aminophosphinomethyl carbene complex 5 has been synthesized. Its conjugated base represents a new chiral cr-unsubstituted amide enolate equivalent for stereoselective addition reactions. The structure of the major diastereoisomer of the aldol addition complex between 5 and pO(2)N-C6H4-CHO, solved by X-ray diffraction, shows that the (S)-enantiomer of the conjugated base of 5 reacts preferentially with the re face of the carbonyl function. (C) 1999 Elsevier Science S.A. All rights reserved
Maiorana, S., Papagni, A., Licandro, E., Perdicchia, D., Baldoli, C., Graiff, C., et al. (1999). Synthesis of the first chiral phosphorous chelate aminophosphino-carbene complex and its applications in stereoselective addition reactions. INORGANICA CHIMICA ACTA, 296(1), 236-245 [10.1016/S0020-1693(99)00372-2].
Synthesis of the first chiral phosphorous chelate aminophosphino-carbene complex and its applications in stereoselective addition reactions
PAPAGNI, ANTONIO;
1999
Abstract
The first phosphorous chelate chiral aminophosphinomethyl carbene complex 5 has been synthesized. Its conjugated base represents a new chiral cr-unsubstituted amide enolate equivalent for stereoselective addition reactions. The structure of the major diastereoisomer of the aldol addition complex between 5 and pO(2)N-C6H4-CHO, solved by X-ray diffraction, shows that the (S)-enantiomer of the conjugated base of 5 reacts preferentially with the re face of the carbonyl function. (C) 1999 Elsevier Science S.A. All rights reserved
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
