Improved insight into cancer cell populations responsible for treatment failure will lead to better outcomes for patients. We herein highlight a single-cell study of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) at diagnosis that revealed hidden developmentally dependent cell signaling states uniquely associated with relapse.

Sarno, J., Davis, K. (2018). Single-cell mass cytometry and machine learning predict relapse in childhood leukemia. MOLECULAR & CELLULAR ONCOLOGY, 5(5) [10.1080/23723556.2018.1472057].

Single-cell mass cytometry and machine learning predict relapse in childhood leukemia

Sarno J.;
2018

Abstract

Improved insight into cancer cell populations responsible for treatment failure will lead to better outcomes for patients. We herein highlight a single-cell study of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) at diagnosis that revealed hidden developmentally dependent cell signaling states uniquely associated with relapse.
Articolo in rivista - Articolo scientifico
cell signaling; Childhood leukemia; innovative methods in molecular and cellular oncology; machine learning; mass cytometry; mechanisms of oncogenesis and tumor progression; mechanisms of resistance to therapy; novel therapeutic targets; prognostic and predictive biomarkers; relapse prediction;
English
2018
5
5
e1472057
none
Sarno, J., Davis, K. (2018). Single-cell mass cytometry and machine learning predict relapse in childhood leukemia. MOLECULAR & CELLULAR ONCOLOGY, 5(5) [10.1080/23723556.2018.1472057].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/524280
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