A CHO cell line and a process for the production of recombinant human urokinase in its low molecular weight form (rh-LMW-uPA) via said cell line are described. The process has high productivity and allows the production of low molecular weight urokinase with improved characteristics in terms of safety, quality and stability.
SOUSA VITOR, L., Righetti, L., Durfort, T., Agostinetto, M., Martellato, D. (2024)Method for the Production of Pharmaceutically Active Recombinant Human Low Molecular Weight Urokinase. . Brevetto No. IT 102023000008805.
Method for the Production of Pharmaceutically Active Recombinant Human Low Molecular Weight Urokinase
DURFORT TIPHANIEMembro del Collaboration Group
;
2024
Abstract
A CHO cell line and a process for the production of recombinant human urokinase in its low molecular weight form (rh-LMW-uPA) via said cell line are described. The process has high productivity and allows the production of low molecular weight urokinase with improved characteristics in terms of safety, quality and stability.
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