Many organisms are in use to test pollutants and their extensive variability clearly emerges from reviews since researchers in the world are involved in continuous effort to set up new assays and to improve those already in use. In the present paper we focus the attention on the mixed function oxidase system and the DNA adduct formation which are two biomarkers widely used and extensively studied in mammals and fish by different Authors. We compare their results with the ones we obtained in amphibians, which result to be a good model. Moreover we present some significative results obtained by the use of cultured cell lines to test the herbicide MCPA.
Camatini, M., Bonfanti, P., Colombo, A., Urani, C. (1998). Molecular approaches to evaluate pollutants. CHEMOSPHERE, 37(14-15), 2717-2738 [10.1016/S0045-6535(98)00316-6].
Molecular approaches to evaluate pollutants
CAMATINI, MARINA CARLA;BONFANTI, PATRIZIA;COLOMBO, ANITA EMILIA;URANI, CHIARA
1998
Abstract
Many organisms are in use to test pollutants and their extensive variability clearly emerges from reviews since researchers in the world are involved in continuous effort to set up new assays and to improve those already in use. In the present paper we focus the attention on the mixed function oxidase system and the DNA adduct formation which are two biomarkers widely used and extensively studied in mammals and fish by different Authors. We compare their results with the ones we obtained in amphibians, which result to be a good model. Moreover we present some significative results obtained by the use of cultured cell lines to test the herbicide MCPA.
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