The present study was designed to provide information on the ability of several different anthropometric markers to reflect the renal impairment associated with body weight increase and to predict the development of renal alterations linked to overweight and obesity. In 574 subjects representative of the general population of the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study, with an age range between 57 and 73 years, we investigated the association between different anthropometric markers of body fat, as alternative to body mass index, and renal failure, to obtain information useful for determining their potential predictive value. Renal dysfunction was significantly associated with almost all anthropometric markers of adiposity related to body weight and body shape. After adjustment for confounders, such as age, sex, office blood pressure, serum glucose, antihypertensive drugs and smoking habit, association remained significant only for waist-to-hip ratio (WHR), lipid accumulation product (LAP) and visceral adiposity index (VAI). These 3 markers also displayed at the receiver operating curves (ROC) analysis the best ability to detect subjects with or without kidney dysfunction. The results of the present study provide evidence that WHR, LAP and VAI represent the best markers of renal dysfunction associated with visceral body fat accumulation.

Vela-Bernal, S., Facchetti, R., Dell'Oro, R., Quarti-Trevano, F., Lurbe, E., Mancia, G., et al. (2023). Anthropometric Measures of Adiposity as Markers of Kidney Dysfunction: A Cross-Sectional Study. HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION, 30(5), 467-474 [10.1007/s40292-023-00600-6].

Anthropometric Measures of Adiposity as Markers of Kidney Dysfunction: A Cross-Sectional Study

Facchetti, Rita;Dell'Oro, Raffaella;Quarti-Trevano, Fosca;Mancia, Giuseppe;Grassi, Guido
2023

Abstract

The present study was designed to provide information on the ability of several different anthropometric markers to reflect the renal impairment associated with body weight increase and to predict the development of renal alterations linked to overweight and obesity. In 574 subjects representative of the general population of the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study, with an age range between 57 and 73 years, we investigated the association between different anthropometric markers of body fat, as alternative to body mass index, and renal failure, to obtain information useful for determining their potential predictive value. Renal dysfunction was significantly associated with almost all anthropometric markers of adiposity related to body weight and body shape. After adjustment for confounders, such as age, sex, office blood pressure, serum glucose, antihypertensive drugs and smoking habit, association remained significant only for waist-to-hip ratio (WHR), lipid accumulation product (LAP) and visceral adiposity index (VAI). These 3 markers also displayed at the receiver operating curves (ROC) analysis the best ability to detect subjects with or without kidney dysfunction. The results of the present study provide evidence that WHR, LAP and VAI represent the best markers of renal dysfunction associated with visceral body fat accumulation.
Articolo in rivista - Articolo scientifico
Epidemiological study; Obesity markers; Renal dysfunction; Waist-to-hip ratio;
English
27-set-2023
2023
30
5
467
474
open
Vela-Bernal, S., Facchetti, R., Dell'Oro, R., Quarti-Trevano, F., Lurbe, E., Mancia, G., et al. (2023). Anthropometric Measures of Adiposity as Markers of Kidney Dysfunction: A Cross-Sectional Study. HIGH BLOOD PRESSURE & CARDIOVASCULAR PREVENTION, 30(5), 467-474 [10.1007/s40292-023-00600-6].
File in questo prodotto:
File Dimensione Formato  
10281-445500_VoR.pdf

accesso aperto

Tipologia di allegato: Publisher’s Version (Version of Record, VoR)
Licenza: Creative Commons
Dimensione 771.95 kB
Formato Adobe PDF
771.95 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/445500
Citazioni
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
Social impact