Objective: To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. Design: Prospective, randomized clinical trial. Setting: Department of surgery in a university hospital. Patients: Two hundred and fifty-seven patients with cancer of the stomach (n = 121), pancreas (n = 110), or esophagus (n = 26) were randomized to receive postoperative total parenteral nutrition (TPN group, n = 131) or early enteral nutrition (EEN group, n = 126). The nutritional goal was 25 kcal/kg/day. The two nutritional formulas were isocaloric and isonitrogenous, and they were continued until oral intake was at least 800 kcal/day. Measurements: Morbidity, mortality, length of hospital stay, and treatment costs were evaluated in all patients. In 40 consecutive patients, selected nutritional, immunologic and inflammatory variables were studied. Moreover, intestinal oxygen tension was evaluated by micropolarographic implantable probes. Main Result...

Braga, M., Gianotti, L., Gentilini, O., Parisi, V., Salis, C., Di Carlo, V. (2001). Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition. CRITICAL CARE MEDICINE, 29(2), 242-248 [10.1097/00003246-200102000-00003].

Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition

Braga, M;GIANOTTI, LUCA VITTORIO;
2001

Abstract

Objective: To evaluate the potential clinical, metabolic, and economic advantages of enteral nutrition over total parenteral nutrition. Design: Prospective, randomized clinical trial. Setting: Department of surgery in a university hospital. Patients: Two hundred and fifty-seven patients with cancer of the stomach (n = 121), pancreas (n = 110), or esophagus (n = 26) were randomized to receive postoperative total parenteral nutrition (TPN group, n = 131) or early enteral nutrition (EEN group, n = 126). The nutritional goal was 25 kcal/kg/day. The two nutritional formulas were isocaloric and isonitrogenous, and they were continued until oral intake was at least 800 kcal/day. Measurements: Morbidity, mortality, length of hospital stay, and treatment costs were evaluated in all patients. In 40 consecutive patients, selected nutritional, immunologic and inflammatory variables were studied. Moreover, intestinal oxygen tension was evaluated by micropolarographic implantable probes. Main Result...
Articolo in rivista - Articolo scientifico
Cancer; Cost; Enteral; Gut; Metabolism; Nutrition; Outcome; Oxygenation; Parenteral; Surgery;
Parenteral Nutrition, Total; Nutrition Assessment; Humans; Esophageal Neoplasms; Pancreatic Neoplasms; Aged; Intestinal Mucosa; Infection; Morbidity; Hyperglycemia; Hospital Mortality; Stomach Neoplasms; Treatment Outcome; Hospital Costs; Male; Postoperative Care; Food, Formulated; Energy Intake; Inflammation; Oxygen; Prospective Studies; Length of Stay; Middle Aged; Female; Enteral Nutrition
English
2001
29
2
242
248
none
Braga, M., Gianotti, L., Gentilini, O., Parisi, V., Salis, C., Di Carlo, V. (2001). Early postoperative enteral nutrition improves gut oxygenation and reduces costs compared with total parenteral nutrition. CRITICAL CARE MEDICINE, 29(2), 242-248 [10.1097/00003246-200102000-00003].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/37512
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