Sacubritil ∗ valsartan (Entresto, Novartis, still commonly referred to as LCZ696) is a combination drug described as a new class of dual-acting angiotensin receptor–neprilysin inhibitor (ARNi). This combination drug has been successfully studied in patients with heart failure with both preserved (HFpEF) and reduced ejection fraction (HFrEF). In this review, the evidences in patients with HFpEF and HFrEF are summarized, including the results of more recent studies.

Gori, M., Volterrani, M., Piepoli, M., Senni, M. (2017). Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs. INTERNATIONAL JOURNAL OF CARDIOLOGY, 226, 136-140 [10.1016/j.ijcard.2016.06.083].

Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs

Senni M
2017

Abstract

Sacubritil ∗ valsartan (Entresto, Novartis, still commonly referred to as LCZ696) is a combination drug described as a new class of dual-acting angiotensin receptor–neprilysin inhibitor (ARNi). This combination drug has been successfully studied in patients with heart failure with both preserved (HFpEF) and reduced ejection fraction (HFrEF). In this review, the evidences in patients with HFpEF and HFrEF are summarized, including the results of more recent studies.
Articolo in rivista - Review Essay
Angiotensin receptor–neprilysin inhibitor; ARNi; Heart failure; LCZ696;
English
23-giu-2016
2017
226
136
140
none
Gori, M., Volterrani, M., Piepoli, M., Senni, M. (2017). Angiotensin receptor-neprilysin inhibitor (ARNi): Clinical studies on a new class of drugs. INTERNATIONAL JOURNAL OF CARDIOLOGY, 226, 136-140 [10.1016/j.ijcard.2016.06.083].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/372359
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