Background: Scarce and non-homogeneous data are available on the prognostic value of clinic heart rate (HR) in coronavirus disease 2019 (COVID-19). Methods: The present study evaluated in 389 patients hospitalized for COVID-19 the in-hospital prognostic value of resting HR, assessed over different time periods, i.e., at hospital admission, during initial 3 days and 7 days of hospitalization. Results: Results show that assessment of this hemodynamic variable during hospitalization provides information on the clinical outcome of the patients, greater HR values being associated with a worse in-hospital prognosis. The prognostic value of elevated HR during COVID-19: 1) was independent on other confounders such as age, gender, comorbidities and fever, 2) appeared to be strengthened by repeated measurements of HR during the initial 3/7 days of hospitalization, and 3) was detectable in patients in which the therapeutic intervention did not include drugs, such as beta-blockers, calcium antagonists, digoxin, ivabradine and antiarrhythmic compounds known to interfere with HR. Conclusions: Heart rate may represent an important marker of a patient’s outcome in COVID-19.

Vanoli, J., Marro, G., Dell'Oro, R., Facchetti, R., Quarti-Trevano, F., Spaziani, D., et al. (2022). Elevated resting heart rate as independent in-hospital prognostic marker in COVID-19. CARDIOLOGY JOURNAL, 29(2), 181-187 [10.5603/CJ.a2022.0009].

Elevated resting heart rate as independent in-hospital prognostic marker in COVID-19

Vanoli, Jennifer
Co-primo
;
Marro, Giacomo
Co-primo
;
Dell'Oro, Raffaella;Facchetti, Rita;Quarti-Trevano, Fosca;Grassi, Guido
Ultimo
2022

Abstract

Background: Scarce and non-homogeneous data are available on the prognostic value of clinic heart rate (HR) in coronavirus disease 2019 (COVID-19). Methods: The present study evaluated in 389 patients hospitalized for COVID-19 the in-hospital prognostic value of resting HR, assessed over different time periods, i.e., at hospital admission, during initial 3 days and 7 days of hospitalization. Results: Results show that assessment of this hemodynamic variable during hospitalization provides information on the clinical outcome of the patients, greater HR values being associated with a worse in-hospital prognosis. The prognostic value of elevated HR during COVID-19: 1) was independent on other confounders such as age, gender, comorbidities and fever, 2) appeared to be strengthened by repeated measurements of HR during the initial 3/7 days of hospitalization, and 3) was detectable in patients in which the therapeutic intervention did not include drugs, such as beta-blockers, calcium antagonists, digoxin, ivabradine and antiarrhythmic compounds known to interfere with HR. Conclusions: Heart rate may represent an important marker of a patient’s outcome in COVID-19.
Articolo in rivista - Articolo scientifico
coronavirus disease 2019 (COVID-19); heart rate; prognosis; sympathetic nervous system;
English
18-feb-2022
2022
29
2
181
187
open
Vanoli, J., Marro, G., Dell'Oro, R., Facchetti, R., Quarti-Trevano, F., Spaziani, D., et al. (2022). Elevated resting heart rate as independent in-hospital prognostic marker in COVID-19. CARDIOLOGY JOURNAL, 29(2), 181-187 [10.5603/CJ.a2022.0009].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/367393
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