Insulin-receptor function in humans is usually studied in vitro on readily available cells, e.g., erythrocytes and fibroblasts. Although these cells are not metabolically important targets for insulin action, information derived from them are often taken as representative of other tissues. The aim of this study was to investigate insulin receptors in vitro on erythrocytes and in vivo on one of the main insulin-target organs, the liver

Dozio, N., Micossi, P., Galimberti, G., Sartori, S., Pozza, G., Dosio, F., et al. (1992). In vivo demonstration of insulin-receptor defect with 123I-labeled insulin and scintigraphic scanning in severe insulin resistance. DIABETES CARE, 15(5), 651-656 [10.2337/diacare.15.5.651].

In vivo demonstration of insulin-receptor defect with 123I-labeled insulin and scintigraphic scanning in severe insulin resistance

GALIMBERTI, GLORIA;FAZIO, FERRUCCIO;
1992

Abstract

Insulin-receptor function in humans is usually studied in vitro on readily available cells, e.g., erythrocytes and fibroblasts. Although these cells are not metabolically important targets for insulin action, information derived from them are often taken as representative of other tissues. The aim of this study was to investigate insulin receptors in vitro on erythrocytes and in vivo on one of the main insulin-target organs, the liver
Articolo in rivista - Articolo scientifico
Heart; Reference Values; Humans; Erythrocytes; Tissue Distribution; Insulin; Kinetics; Liver; Iodine Radioisotopes; Insulin Resistance; Adolescent; Receptor, Insulin; Female; Male; Myocardium
English
1992
15
5
651
656
none
Dozio, N., Micossi, P., Galimberti, G., Sartori, S., Pozza, G., Dosio, F., et al. (1992). In vivo demonstration of insulin-receptor defect with 123I-labeled insulin and scintigraphic scanning in severe insulin resistance. DIABETES CARE, 15(5), 651-656 [10.2337/diacare.15.5.651].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/35373
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