This retrospective study aims to assess cognitive involvement in pre-AIDS, not drug abuser subjects and to determine whether CD4 status or disease stage best correlates with cognitive changes that may portend development of ADC. 328 cases were analyzed. no differences in psychometric performance in relation to CDC stage were found. instead , patients with CD4<200/ul performed worse overall, with a statistically significant difference for Digit Symbol, Corsi Test, Block Design and HIVDA Scale. even if cognitive decline is not evident in the early phase of HIV infection, CD4 count seems the more sensitive early indicator of cognitive changes adequately pointed out by the HIVDA Scale, which could be considered a useful screening tool for cognitive deficit.

Grassi, M., Perin, C., Borella, M., Mangoni, A. (1999). Assessment of cognitive function in asymptomatic HIV-positive subjects. EUROPEAN NEUROLOGY, 42(4), 225-229 [10.1159/000008112].

Assessment of cognitive function in asymptomatic HIV-positive subjects

PERIN, CECILIA;
1999

Abstract

This retrospective study aims to assess cognitive involvement in pre-AIDS, not drug abuser subjects and to determine whether CD4 status or disease stage best correlates with cognitive changes that may portend development of ADC. 328 cases were analyzed. no differences in psychometric performance in relation to CDC stage were found. instead , patients with CD4<200/ul performed worse overall, with a statistically significant difference for Digit Symbol, Corsi Test, Block Design and HIVDA Scale. even if cognitive decline is not evident in the early phase of HIV infection, CD4 count seems the more sensitive early indicator of cognitive changes adequately pointed out by the HIVDA Scale, which could be considered a useful screening tool for cognitive deficit.
Articolo in rivista - Articolo scientifico
neuropsychological assessment, cognitive function, HIV, disease stage, CD4 count
English
1999
42
4
225
229
none
Grassi, M., Perin, C., Borella, M., Mangoni, A. (1999). Assessment of cognitive function in asymptomatic HIV-positive subjects. EUROPEAN NEUROLOGY, 42(4), 225-229 [10.1159/000008112].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/35094
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