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Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.
Roth, G., Mensah, G., Johnson, C., Addolorato, G., Ammirati, E., Baddour, L., et al. (2020). Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 76(25), 2982-3021 [10.1016/j.jacc.2020.11.010].
Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study
Roth G. A.
;Mensah G. A.
;Johnson C. O.;Addolorato G.;Ammirati E.;Baddour L. M.;Barengo N. C.;Beaton A. Z.;Benjamin E. J.;Benziger C. P.;Bonny A.;Brauer M.;Brodmann M.;Cahill T. J.;Carapetis J.;Catapano A. L.;Chugh S. S.;Cooper L. T.;Coresh J.;Criqui M.;DeCleene N.;Eagle K. A.;Emmons-Bell S.;Feigin V. L.;Fernandez-Sola J.;Fowkes G.;Gakidou E.;Grundy S. M.;He F. J.;Howard G.;Hu F.;Inker L.;Karthikeyan G.;Kassebaum N.;Koroshetz W.;Lavie C.;Lloyd-Jones D.;Lu H. S.;Mirijello A.;Temesgen A. M.;Mokdad A.;Moran A. E.;Muntner P.;Narula J.;Neal B.;Ntsekhe M.;Moraes de Oliveira G.;Otto C.;Owolabi M.;Pratt M.;Rajagopalan S.;Reitsma M.;Ribeiro A. L. P.;Rigotti N.;Rodgers A.;Sable C.;Shakil S.;Sliwa-Hahnle K.;Stark B.;Sundstrom J.;Timpel P.;Tleyjeh I. M.;Valgimigli M.;Vos T.;Whelton P. K.;Yacoub M.;Zuhlke L.;Murray C.;Fuster V.;Barengo N. C.;Beaton A.;Bonny A.;Carapetis J. R.;Chugh S.;Criqui M. H.;DeCleene N. K.;Fernandez-Sola J.;Fowkes F. G. R.;Kassebaum N. J.;Koroshetz W. J.;Misganaw A. T.;Mokdad A. H.;Oliveira G. M. M.;Otto C. M.;Owolabi M. O.;Reitsma M. B.;Rigotti N. A.;Sable C. A.;Shakil S. S.;Sliwa K.;Stark B. A.;Tleyjeh I. I.;Zuhlke L. J.;Abbasi-Kangevari M.;Abdi A.;Abedi A.;Aboyans V.;Abrha W. A.;Abu-Gharbieh E.;Abushouk A. I.;Acharya D.;Adair T.;Adebayo O. M.;Ademi Z.;Advani S. M.;Afshari K.;Afshin A.;Agarwal G.;Agasthi P.;Ahmad S.;Ahmadi S.;Ahmed M. B.;Aji B.;Akalu Y.;Akande-Sholabi W.;Aklilu A.;Akunna C. J.;Alahdab F.;Al-Eyadhy A.;Alhabib K. F.;Alif S. M.;Alipour V.;Aljunid S. M.;Alla F.;Almasi-Hashiani A.;Almustanyir S.;Al-Raddadi R. M.;Amegah A. K.;Amini S.;Aminorroaya A.;Amu H.;Amugsi D. A.;Ancuceanu R.;Anderlini D.;Andrei T.;Andrei C. L.;Ansari-Moghaddam A.;Anteneh Z. A.;Antonazzo I. C.;Antony B.;Anwer R.;Appiah L. T.;Arabloo J.;Arnlov J.;Artanti K. D.;Ataro Z.;Ausloos M.;Avila-Burgos L.;Awan A. T.;Awoke M. A.;Ayele H. T.;Ayza M. A.;Azari S.;B D. B.;Baheiraei N.;Baig A. A.;Bakhtiari A.;Banach M.;Banik P. C.;Baptista E. A.;Barboza M. A.;Barua L.;Basu S.;Bedi N.;Bejot Y.;Bennett D. A.;Bensenor I. M.;Berman A. E.;Bezabih Y. M.;Bhagavathula A. S.;Bhaskar S.;Bhattacharyya K.;Bijani A.;Bikbov B.;Birhanu M. M.;Boloor A.;Brant L. C.;Brenner H.;Briko N. I.;Butt Z. A.;Caetano dos Santos F. L.;Cahill L. E.;Cahuana-Hurtado L.;Camera L. A.;Campos-Nonato I. R.;Cantu-Brito C.;Car J.;Carrero J. J.;Carvalho F.;Castaneda-Orjuela C. A.;Catala-Lopez F.;Cerin E.;Charan J.;Chattu V. K.;Chen S.;Chin K. L.;Choi J. -Y. J.;Chu D. -T.;Chung S. -C.;Cirillo M.;Coffey S.;Conti S.;Costa V. M.;Cundiff D. K.;Dadras O.;Dagnew B.;Dai X.;Damasceno A. A. M.;Dandona L.;Dandona R.;Davletov K.;De la Cruz-Gongora V.;De la Hoz F. P.;De Neve J. -W.;Denova-Gutierrez E.;Derbew Molla M.;Derseh B. T.;Desai R.;Deuschl G.;Dharmaratne S. D.;Dhimal M.;Dhungana R. R.;Dianatinasab M.;Diaz D.;Djalalinia S.;Dokova K.;Douiri A.;Duncan B. B.;Duraes A. R.;Eagan A. W.;Ebtehaj S.;Eftekhari A.;Eftekharzadeh S.;Ekholuenetale M.;El Nahas N.;Elgendy I. Y.;Elhadi M.;El-Jaafary S. I.;Esteghamati S.;Etisso A. E.;Eyawo O.;Fadhil I.;Faraon E. J. A.;Faris P. S.;Farwati M.;Farzadfar F.;Fernandes E.;Fernandez Prendes C.;Ferrara P.;Filip I.;Fischer F.;Flood D.;Fukumoto T.;Gad M. M.;Gaidhane S.;Ganji M.;Garg J.;Gebre A. K.;Gebregiorgis B. G.;Gebregzabiher K. Z.;Gebremeskel G. G.;Getacher L.;Obsa A. G.;Ghajar A.;Ghashghaee A.;Ghith N.;Giampaoli S.;Gilani S. A.;Gill P. S.;Gillum R. F.;Glushkova E. V.;Gnedovskaya E. V.;Golechha M.;Gonfa K. B.;Goudarzian A. H.;Goulart A. C.;Guadamuz J. S.;Guha A.;Guo Y.;Gupta R.;Hachinski V.;Hafezi-Nejad N.;Haile T. G.;Hamadeh R. R.;Hamidi S.;Hankey G. J.;Hargono A.;Hartono R. K.;Hashemian M.;Hashi A.;Hassan S.;Hassen H. Y.;Havmoeller R. J.;Hay S. I.;Hayat K.;Heidari G.;Herteliu C.;Holla R.;Hosseini M.;Hosseinzadeh M.;Hostiuc M.;Hostiuc S.;Househ M.;Huang J.;Humayun A.;Iavicoli I.;Ibeneme C. U.;Ibitoye S. E.;Ilesanmi O. S.;Ilic I. M.;Ilic M. D.;Iqbal U.;Irvani S. S. N.;Islam S. M. S.;Islam R. M.;Iso H.;Iwagami M.;Jain V.;Javaheri T.;Jayapal S. K.;Jayaram S.;Jayawardena R.;Jeemon P.;Jha R. P.;Jonas J. B.;Jonnagaddala J.;Joukar F.;Jozwiak J. J.;Jurisson M.;Kabir A.;Kahlon T.;Kalani R.;Kalhor R.;Kamath A.;Kamel I.;Kandel H.;Kandel A.;Karch A.;Kasa A. S.;Katoto P. D. M. C.;Kayode G. A.;Khader Y. S.;Khammarnia M.;Khan M. S.;Khan M. N.;Khan M.;Khan E. A.;Khatab K.;Kibria G. M. A.;Kim Y. J.;Kim G. R.;Kimokoti R. W.;Kisa S.;Kisa A.;Kivimaki M.;Kolte D.;Koolivand A.;Korshunov V. A.;Koulmane Laxminarayana S. L.;Koyanagi A.;Krishan K.;Krishnamoorthy V.;Kuate Defo B.;Kucuk Bicer B.;Kulkarni V.;Kumar G. A.;Kumar N.;Kurmi O. P.;Kusuma D.;Kwan G. F.;La Vecchia C.;Lacey B.;Lallukka T.;Lan Q.;Lasrado S.;Lassi Z. S.;Lauriola P.;Lawrence W. R.;Laxmaiah A.;LeGrand K. E.;Li M. -C.;Li B.;Li S.;Lim S. S.;Lim L. -L.;Lin H.;Lin Z.;Lin R. -T.;Liu X.;Lopez A. D.;Lorkowski S.;Lotufo P. A.;Lugo A.;M N. K.;Madotto F.;Mahmoudi M.;Majeed A.;Malekzadeh R.;Malik A. A.;Mamun A. A.;Manafi N.;Mansournia M. A.;Mantovani L. G.;Martini S.;Mathur M. R.;Mazzaglia G.;Mehata S.;Mehndiratta M. M.;Meier T.;Menezes R. G.;Meretoja A.;Mestrovic T.;Miazgowski B.;Miazgowski T.;Michalek I. M.;Miller T. R.;Mirrakhimov E. M.;Mirzaei H.;Moazen B.;Moghadaszadeh M.;Mohammad Y.;Mohammad D. K.;Mohammed S.;Mohammed M. A.;Mokhayeri Y.;Molokhia M.;Montasir A. A.;Moradi G.;Moradzadeh R.;Moraga P.;Morawska L.;Moreno Velasquez I.;Morze J.;Mubarik S.;Muruet W.;Musa K. I.;Nagarajan A. J.;Nalini M.;Nangia V.;Naqvi A. A.;Narasimha Swamy S.;Nascimento B. R.;Nayak V. C.;Nazari J.;Nazarzadeh M.;Negoi R. I.;Neupane Kandel S.;Nguyen H. L. T.;Nixon M. R.;Norrving B.;Noubiap J. J.;Nouthe B. E.;Nowak C.;Odukoya O. O.;Ogbo F. A.;Olagunju A. T.;Orru H.;Ortiz A.;Ostroff S. M.;Padubidri J. R.;Palladino R.;Pana A.;Panda-Jonas S.;Parekh U.;Park E. -C.;Parvizi M.;Pashazadeh Kan F.;Patel U. K.;Pathak M.;Paudel R.;Pepito V. C. F.;Perianayagam A.;Perico N.;Pham H. Q.;Pilgrim T.;Piradov M. A.;Pishgar F.;Podder V.;Polibin R. V.;Pourshams A.;Pribadi D. R. A.;Rabiee N.;Rabiee M.;Radfar A.;Rafiei A.;Rahim F.;Rahimi-Movaghar V.;Ur Rahman M. H.;Rahman M. A.;Rahmani A. M.;Rakovac I.;Ram P.;Ramalingam S.;Rana J.;Ranasinghe P.;Rao S. J.;Rathi P.;Rawal L.;Rawasia W. F.;Rawassizadeh R.;Remuzzi G.;Renzaho A. M. N.;Rezapour A.;Riahi S. M.;Roberts-Thomson R. L.;Roever L.;Rohloff P.;Romoli M.;Roshandel G.;Rwegerera G. M.;Saadatagah S.;Saber-Ayad M. M.;Sabour S.;Sacco S.;Sadeghi M.;Saeedi Moghaddam S.;Safari S.;Sahebkar A.;Salehi S.;Salimzadeh H.;Samaei M.;Samy A. M.;Santos I. S.;Santric-Milicevic M. M.;Sarrafzadegan N.;Sarveazad A.;Sathish T.;Sawhney M.;Saylan M.;Schmidt M. I.;Schutte A. E.;Senthilkumaran S.;Sepanlou S. G.;Sha F.;Shahabi S.;Shahid I.;Shaikh M. A.;Shamali M.;Shamsizadeh M.;Shawon M. S. R.;Sheikh A.;Shigematsu M.;Shin M. -J.;Shin J. I.;Shiri R.;Shiue I.;Shuval K.;Siabani S.;Siddiqi T. J.;Silva D. A. S.;Singh J. A.;Mtech A. S.;Skryabin V. Y.;Skryabina A. A.;Soheili A.;Spurlock E. E.;Stockfelt L.;Stortecky S.;Stranges S.;Suliankatchi Abdulkader R.;Tadbiri H.;Tadesse E. G.;Tadesse D. B.;Tajdini M.;Tariqujjaman M.;Teklehaimanot B. F.;Temsah M. -H.;Tesema A. K.;Thakur B.;Thankappan K. R.;Thapar R.;Thrift A. G.;Timalsina B.;Tonelli M.;Touvier M.;Tovani-Palone M. R.;Tripathi A.;Tripathy J. P.;Truelsen T. C.;Tsegay G. M.;Tsegaye G. W.;Tsilimparis N.;Tusa B. S.;Tyrovolas S.;Umapathi K. K.;Unim B.;Unnikrishnan B.;Usman M. S.;Vaduganathan M.;Valdez P. R.;Vasankari T. J.;Velazquez D. Z.;Venketasubramanian N.;Vu G. T.;Vujcic I. S.;Waheed Y.;Wang Y.;Wang F.;Wei J.;Weintraub R. G.;Weldemariam A. H.;Westerman R.;Winkler A. S.;Wiysonge C. S.;Wolfe C. D. A.;Wubishet B. L.;Xu G.;Yadollahpour A.;Yamagishi K.;Yan L. L.;Yandrapalli S.;Yano Y.;Yatsuya H.;Yeheyis T. Y.;Yeshaw Y.;Yilgwan C. S.;Yonemoto N.;Yu C.;Yusefzadeh H.;Zachariah G.;Zaman S. B.;Zaman M. S.;Zamanian M.;Zand R.;Zandifar A.;Zarghi A.;Zastrozhin M. S.;Zastrozhina A.;Zhang Z. -J.;Zhang Y.;Zhang W.;Zhong C.;Zou Z.;Zuniga Y. M. H.;Murray C. J. L.
2020
Abstract
Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.
Roth, G., Mensah, G., Johnson, C., Addolorato, G., Ammirati, E., Baddour, L., et al. (2020). Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 76(25), 2982-3021 [10.1016/j.jacc.2020.11.010].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/303602
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simulazione ASN
Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande.
La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 598/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.
