Ifosfamide and doxorubicin are the most active agents in the treatment of sarcomas and are characterized by a marked dose-response relationship. The objective of this study was to determine the maximum tolerated dose (MTD) of both agents in combination under granulocyte-macrophage colony-stimulating factor (GM-CSF) cover.

Leyvraz, S., Bacchi, M., Cerny, T., Lissoni, A., Sessa, C., Bressoud, A., et al. (1998). Phase I multicenter study of combined high-dose ifosfamide and doxorubicin in the treatment of advanced sarcomas. ANNALS OF ONCOLOGY, 9(8), 877-884 [10.1023/A:1008464504583].

Phase I multicenter study of combined high-dose ifosfamide and doxorubicin in the treatment of advanced sarcomas

LISSONI, ANDREA ALBERTO;
1998

Abstract

Ifosfamide and doxorubicin are the most active agents in the treatment of sarcomas and are characterized by a marked dose-response relationship. The objective of this study was to determine the maximum tolerated dose (MTD) of both agents in combination under granulocyte-macrophage colony-stimulating factor (GM-CSF) cover.
Articolo in rivista - Articolo scientifico
Treatment Outcome; Male; Adolescent; Sarcoma; Middle Aged; Granulocyte-Macrophage Colony-Stimulating Factor; Survival Analysis; Ifosfamide; Female; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Infusions, Intravenous; Antineoplastic Combined Chemotherapy Protocols; Soft Tissue Neoplasms; Aged; Adult; Genital Neoplasms, Female; Drug Administration Schedule; Bone Neoplasms; Doxorubicin
English
ago-1998
9
8
877
884
none
Leyvraz, S., Bacchi, M., Cerny, T., Lissoni, A., Sessa, C., Bressoud, A., et al. (1998). Phase I multicenter study of combined high-dose ifosfamide and doxorubicin in the treatment of advanced sarcomas. ANNALS OF ONCOLOGY, 9(8), 877-884 [10.1023/A:1008464504583].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10281/30073
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