A composite model, describing the glucose/insulin dynamics following daily food administration and insulin injections in Type 1 Diabetes Mellitus patients is presented. Three daily meals have been simulated, food intake representing four different types of foodstuffs, along with three rapid-acting insulin injections and one long-acting insulin injection. Three different scenarios (depending on whether food intake and/or administration times were fixed or random) were hypothesized: simulations show a very realistic time-course for both glucose and insulin dynamics over long (20 days) and short (one day) time periods.
Panunzi, S., Borri, A., Palumbo, P., Kovacs, L., De Gaetano, A. (2014). Simulation of insulin regimen and glucose profiles in Type 1 Diabetic Patient. In Proceedings of IEEE Conference on Systems, Man and Cybernetics (SMC), San Diego (CA, USA), 5-8 October 2014 (pp.2464-2469). IEEE Institute of Electrical and Electronics Engineers [10.1109/smc.2014.6974296].
Simulation of insulin regimen and glucose profiles in Type 1 Diabetic Patient
Palumbo P;
2014
Abstract
A composite model, describing the glucose/insulin dynamics following daily food administration and insulin injections in Type 1 Diabetes Mellitus patients is presented. Three daily meals have been simulated, food intake representing four different types of foodstuffs, along with three rapid-acting insulin injections and one long-acting insulin injection. Three different scenarios (depending on whether food intake and/or administration times were fixed or random) were hypothesized: simulations show a very realistic time-course for both glucose and insulin dynamics over long (20 days) and short (one day) time periods.File | Dimensione | Formato | |
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2014-11 ICSMC-San Diego - T1DM glucose profiles.pdf
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