Background: Immunosuppressive therapy has been - until the recent release of new guidelines on diagnosis and management - the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. Case presentation: We report the occurrence of idiopathic pulmonary fibrosis in a white man receiving chronic immunosuppressive treatment following a heart transplant. Conclusions: This case report suggests that the immune mechanisms targeted by azathioprine and cyclosporine do not play a role in the pathogenesis of idiopathic pulmonary fibrosis.
Cerri, S., Sgalla, G., Richeldi, L., Luppi, F. (2016). Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: A case report. JOURNAL OF MEDICAL CASE REPORTS, 10(1), 127 [10.1186/s13256-016-0916-5].
Occurrence of idiopathic pulmonary fibrosis during immunosuppressive treatment: A case report
Luppi, F
2016
Abstract
Background: Immunosuppressive therapy has been - until the recent release of new guidelines on diagnosis and management - the recommended treatment for idiopathic pulmonary fibrosis. However, its efficacy in patients with idiopathic pulmonary fibrosis has always been a matter of debate. Case presentation: We report the occurrence of idiopathic pulmonary fibrosis in a white man receiving chronic immunosuppressive treatment following a heart transplant. Conclusions: This case report suggests that the immune mechanisms targeted by azathioprine and cyclosporine do not play a role in the pathogenesis of idiopathic pulmonary fibrosis.
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