Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.
Pirola, E., Vergani, F., Casiraghi, P., Leone, E., Guerra, P., Sganzerla, E., et al. (2009). Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine. JOURNAL OF NEUROSURGERY. SPINE, 10(4), 329-333 [10.3171/2009.1.SPINE08351].
Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine
PIROLA, ELENA;VERGANI, FRANCESCO;CASIRAGHI, PAOLO;SGANZERLA, ERIK PIETRO;LEONE, BIAGIO EUGENIO
2009
Abstract
Phosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.
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